Table of Contents

Preface

Chapter 1. Building and Sustaining a Comprehensive Pediatric Oncology Care Team: The Roles and Integration of Psychosocial and Rehabilitative Team Members
Katherine Price PsyD,¹ Amy Downes Westfall, OTD, OTR/L,² Rev. Connie Beemer, MDiv, BCC,³
Linda H. Casper, MS,⁴ Daphne Dierkes, ATR, LPC,⁴ Erin M. Hickey, MD,^5,6 Kristin M. Kueper, MS, RD, CSP, LD,⁷ Tyler Robertson, MA, CCLS,⁴ and Rebecca H. Foster, PhD^1,6
1Department of Psychology, St. Louis Children’s Hospital, St. Louis, MO, USA
²Department of Therapy and Audiology Services, St. Louis Children’s Hospital, St. Louis, MO, USA
³Department of Chaplaincy and Social Work, St. Louis Children’s Hospital, St. Louis, MO, USA
⁴Department of Child Life Services, St. Louis Children’s Hospital, St. Louis, MO, USA
⁵Department of Newborn Medicine, St. Louis Children’s Hospital, St. Louis, MO, USA ⁶Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA
⁷Department of Nutrition Services, St. Louis Children’s Hospital, St. Louis, MO, USA

Chapter 2. Recent Advances in Manufacturing of Chimeric Antigen Receptor T Cells for Cancer Therapy
Sena Dere¹, Alison Greteman¹ and Dharmakeerthi Nawarathna^1,2
1Biomedical Engineering program, North Dakota State University, Fargo, ND, USA
²Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND, USA

Chapter 3. Alterations of Epigenetic Gene Expression Regulation in Thyroid Cancerogenesis
Branislav Rovcanin, MD, PhD
University of Belgrade, Faculty of Medicine, University Clinical Center of Serbia, Clinic for Endocrine Surgery, Belgrade, Serbia

Chapter 4. Alternative Target Pathways for Putative Therapeutic Approaches Affecting Chronic Myeloid Leukemia Cells
L. P. Shvachko¹, S. V. Antonenko¹, D. S. Guryanov¹, M. P. Zavelevich², D. F. Gluzman²
and G. D. Telegeev^1
1Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine
²RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine

Chapter 5. Paclitaxel Resistance in Head and Neck Cancer: Underlying Molecular Mechanisms and Potential Therapeutic Targets to Overcome Paclitaxel Resistance
Abdulmelik Aytatli^1,2 and Omer Faruk Karatas^1,2
1Molecular Biology and Genetics Department, Erzurum Technical University,
Erzurum, Turkey
²High Technology Application and Research Center, Erzurum Technical University, Erzurum, Turkey

Chapter 6. Inhibition of Autophagy for Instigating Temozolomide for Increasing Induction of Apoptosis in Glioblastoma
Evan D. Wilson and Swapan K. Ray
Department of Pathology, Microbiology, and Immunology, University of South Carolina School of Medicine, Columbia, SC, USA

Chapter 7.  Ectopic Placental-Like Alkaline Phosphatase (PLAP) Reprogramming to Differentiation by Vitamin E Exposure in Leukemic K562 Cells
L. P. Shvachko¹, M. P. Zavelevich², D. F. Gluzman² and G. D. Telegeev^1
1Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine
²RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of NASU, Kyiv, Ukraine

Chapter 8. New Molecular Studies for Approaches Affecting Chronic Myeloid Leukemia Cells to Differentiation Pathways
L. P. Shvachko¹, M. P. Zavelevich², D. F. Glusman² and G. D. Telegeev^1
1Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine
²R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine

Index