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Patrycja Dębska, David Aebisher and Dorota Bartusik-Aebisher
Medical College of The University of Rzeszów, Rzeszów, Poland
Part of the book: The Biochemical Guide to Enzymes
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one of the enzymes from the oxidoreductase class. There is one functional gene in the human body that codes for GAPDH, which is located on the 12th chromosome.
Keywords: glyceraldehyde-3-phosphate, chromosome, cellular proteins
Kosova A. A., Khodyreva S. N., Lavrik O. I. Role of Glyceraldehyde-3-Phosphate
Dehydrogenase (GAPDH) in DNA Repair. Biochemistry (Mosc). 2017 Jun;82(6):643-654.
Muronetz V. I., Barinova K. V., Stroylova Y. Y., Semenyuk P. I., Schmalhausen E. V.
Glyceraldehyde-3-phosphate dehydrogenase: Aggregation mechanisms and impact on
amyloid neurodegenerative diseases. Int J Biol Macromol. 2017 Jul;100:55-66.
Muronetz V. I., Melnikova A. K., Barinova K. V., Schmalhausen E. V. Inhibitors of
Glyceraldehyde 3-Phosphate Dehydrogenase and Unexpected Effects of Its Reduced
Activity. Biochemistry (Mosc). 2019 Nov;84(11):1268-1279.
Sirover M. A. Moonlighting glyceraldehyde-3-phosphate dehydrogenase: posttranslational
modification, protein and nucleic acid interactions in normal cells and in human
pathology. Crit Rev Biochem Mol Biol. 2020 Aug;55(4):354-371.
White M. R., Garcin E. D. D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and
Function. Subcell Biochem. 2017;83:413-453.
We publish over 800 titles annually by leading researchers from around the world. Submit a Book Proposal Now!