Adamo Federica, David Aebisher and Dorota Bartusik-Aebisher
Medical College of the University of Rzeszów, Poland

Part of the book: The Biochemical Guide to Enzymes

Abstract

Photodynamic therapy (or PDT) undoubtedly represents one of the most innovative, modern and technologically advanced dermatological therapies currently available. Initially introduced for the treatment of pre[1]cancerous lesions and for skin tumors deriving from the epidermis (and therefore not melanocytic), photodynamic therapy has been used to treat an increasingly broad spectrum of skin conditions, both pathological and aesthetic (the so-called photorejuvenation). Based on the use of a sensitizing agent, PDT uses a particular light source to obtain its therapeutic and cosmetic effects. From light, therefore, the cause of these types of injuries and skin aging, science has developed a technique that, through light itself, brings health and beauty to the skin.

Keyword: photodynamic therapy, mechanism, biochemistry

References

Dobson J, de Queiroz GF, Golding JP. Photodynamic therapy and diagnosis: Principles and
comparative aspects. Vet J. 2018; 233: 8-18.
Kwiatkowski S, Knap B, Przystupski D, Saczko J, Kędzierska E, Knap-Czop K, Kotlińska
J, Michel O, Kotowski K, Kulbacka J. Photodynamic therapy – mechanisms,
photosensitizers and combinations. Biomed Pharmacother. 2018; 106: 1098-1107.
Plotino G, Grande NM, Mercade M. Photodynamic therapy in endodontics. Int Endod J.
2019; 52(6): 760-774.
Warrier A, Mazumder N, Prabhu S, Satyamoorthy K, Murali TS. Photodynamic therapy to
control microbial biofilms. Photodiagnosis Photodyn Ther. 2021; 33: 102090.
Zhang Q, Li L. Photodynamic combinational therapy in cancer treatment. J BUON. 2018;
23(3): 561-567.