Table of Contents
Table of Contents
Preface
Chapter 1. Anti-Obesity Drugs against Fat Absorption: Current Status and Future Prospects of Lipase Inhibitors
(Giovanni Ortiz Leoncini, PhD, Nathan Araújo de Melo, João Xavier de Araújo-Júnior, PhD, Pharmaceutical Sciences Institute, Federal University of Alagoas, Maceió, Alagoas, and others)
Chapter 2. Medicinal Chemistry of Modulation of Bacterial Resistance by Inhibition of Efflux Systems
(Pedro Gregório Vieira Aquino, PhD, Federal Rural University of Pernambuco, Garanhuns, Brazil)
Chapter 3. The Role of Thiophene Core in Medicinal Chemistry of Neglected Tropical Diseases
(Igor José dos Santos Nascimento, PhD, Paulo Fernando da Silva Santos Júnior, PhD, Rodrigo Santos Aquino de Araújo, PhD, Francisco Jaime B. Mendonça-Junior, PhD, and Thiago Mendonça de Aquino, PhD, Laboratory of Medicinal Chemistry, Federal University of Alagoas, Maceió, Brazil, and others)
Chapter 4. Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer′S Agents
(Phuong-Thao Tran, PhD, and Van-Hai Hoang, PhD, Department of Pharmaceutical Chemistry, Hanoi University of Pharmacy, Hanoi, Vietnam, and others)
Chapter 5. Cancer and Computational Medicinal Chemistry: Advances and Perspectives in Drug Discovery and Design
(Rafaela Molina de Angelo, MD, Heberth de Paula, PhD, Sheila Cruz Araujo, PhD, Michell Oliveira Almeida, PhD, Simone Queiroz Pantaleão, PhD, Kathia Maria Honorio, PhD, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil, and others)
Chapter 6. Indoleamine 2,3-Dioxygenase 1 Inhibitors: Discovery, Development, and Promise in Cancer Immunotherapy
(Van-Hai Hoang and Phuong-Thao Tran, Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Science, College of Pharmacy, Seoul National University, Seoul, Korea, and others)
Chapter 7. An Update on Eg5 Kinesin Inhibitors for the Treatment of Cancer
(Paolo Guglielmi, PhD, Daniela Secci, PhD, Giulia Rotondi, Simone Carradori, PhD, Departmento of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, P.le A. Moro 5, Rome, Italy, and others)
Index
Reviews
“This book covers hot current topics in medicinal chemistry, using a molecular-based approach, providing us with knowledge on new and valuable targets, on corresponding active synthetic and natural products, and deserves to be read by a broad audience, providing a rich food for thought.” – Dr. Marilia O. Fonseca Goulart, Professor, Federal University of Alagoas – Brazil.
Audience
Contents are addressed to who has an interest in the medicinal chemistry field. The knowledge and text inside this book are readable to anyone from Pharmacy and Medical Sciences. However, it is focused on the undergraduate and postgraduate students, as well as, professors and researchers from Universities worldwide.
Keywords: Medicinal chemistry, drug design, Alzheimer, multidrug-resistance, cancer
