Life Sciences – Nova Science Publishers https://novapublishers.com Publisher of Books and Journals in Medicine and Health, Science and Technology and Social Sciences Thu, 09 Feb 2023 16:00:11 +0000 en-US hourly 1 https://wordpress.org/?v=6.1.1 https://novapublishers.com/wp-content/uploads/2018/08/cropped-nova-favicon-32x32.jpg Life Sciences – Nova Science Publishers https://novapublishers.com 32 32 Terminal Philosophy Syndrome – Ecology and the Imponderable https://novapublishers.com/shop/terminal-philosophy-syndrome-ecology-and-the-imponderable/ Sat, 24 Dec 2022 21:36:06 +0000 https://novapublishers.com/?post_type=product&p=140935 Series: Human Evolution, Biological and Cultural Domains BISAC: NAT010000; PHI006000; SCI100000 DOI: 10.52305/CZHM8078
"A phenomenally thorough and insightful book that deserves to be read and re-read by everyone who has seriously contemplated the possibility that we are at the threshold of our own species-extinction...This is not an easy book to read, and it is even harder to put it down once I started reading it. But reading it is worth the effort. Not because it tells us what our fate will be, but because it clears the deck of our inquiring mind so we can try to find our way toward an answer we can reasonably believe in. I am grateful to Michael Tobias and Jane Morrison for a seminal book." - Dr. Ervin Laszlo, Author, Philosopher and Systems Scientist Terminal Philosophy Syndrome - Ecology and the Imponderable is an important book. It provides us with a clear roadmap of what we are doing to the world, what we are doing to each other, what we are doing to Nature. But the roadmap is couched in a velvet glove of intellectual delights about the views of philosophers, religious leaders, and power-hungry rulers who have placed human interests first, above Nature which sustains us and makes our lives possible. The book can be read on two levels. One is the level of admiration for the depth of scholarship and complex thought. The other level is a wake-up call: We can all change, or we can all die. A great book!" - Dr. Con Slobodchikoff, Author of Chasing Doctor Dolittle: Learning the Language of Animals (St. Martin’s Press, 2012); Professor Emeritus of Biology, Northern Arizona University, CEO of Zoolingua, CEO of Animal Communications Ltd., Director, Animal Language Institute; Lead author, Prairie Dogs: Communication and Community in an Animal Society (Harvard University Press, 2009) “Reading Tobias’ and Morrison’s tome brought to mind the English biologist Thomas Henry Huxley’s words, “Sit down before fact as a little child, be prepared to give up every preconceived notion, follow humbly wherever and to whatever abysses nature leads, or you shall learn nothing.” Cancel your appointments, avail yourself of a comfortable chair, and appreciate it as you might a slow walk in a dense forest, the ground of which is thick with acorns and buds, the air filled with the sound of birds talking about their experiences, each an “Other” that carries inside their being wisdom about life and how to live it as a part of the whole. It’s an awe-inspiring read.” - Ingrid Newkirk, Founder and President of People for the Ethical Treatment of Animals (PETA) and its international affiliates. A Forbes Person of the Year, Ms. Newkirk is the author of 14 books on animals, their abilities, language, and sentience, and the subject of the HBO documentary, “I Am an Animal.” "This staggering work of erudition and passion, Terminal Philosophy Syndrome - Ecology and the Imponderable, points the finger to the human as catalyst for countless ways of self-destruction and devastation of innumerable forms of non-humans. What can be done? How can we even recognize our complicity in so many tragedies, from the Holocaust and the many events before and since including the invasion of Ukraine and the ongoing slaughter of billions of animals each year to slake unquenched human hunger? Tobias and Morrison call for a mind shift, a radical move from passivity to bold changes in thinking and lifestyle. By itemizing the scope and scale of our current global emergency in the context of a long and brutal history, this book serves as a powerful incentive to stand up and be counted, and to commit oneself personally to be part of the needed solutions. Tobias and Morrison’s encounter with Putin underlines the fragility and limits and urgency of human agency. The question remains: will the examples of Jain austere living and Bhutan’s good government be enough to provide a roadmap into an uncertain future?" - Dr. Christopher Key Chapple, Doshi Professor of Indic and Comparative Theology and Founding Director of the Master of Arts in Yoga Studies at Loyola Marymount University, Los Angeles, California, USA "Terminal Philosophy Syndrome is a timely work of genius - a culmination of the brilliant, methodological, visionary but most importantly, radically compassionate, highly attuned thinking of Michael Charles Tobias and Jane Gray Morrison. Their rarified yet devastating treatise explores the sobering, if terminal nexus between ecological conscience and our historical incapacity as a species to meaningfully reconfigure the nature of who we are as uncontrollable biodiversity and earth destroyers. Tobias and Morrison have, like the Webb telescope, implored the farthest reaches of an imponderable possibility for human consciousness to “exceed its grasp,” innovating paradigms beyond atavistic linguistic and philosophical bounds, and enjoin ourselves with Nature in selfless, biosemiospheric immanence. A must read for the deepest of deep ecologists!" - Michael Bostick, Artist, Freelance Writer and Senior Climate and Environmental Professional, San Francisco, CA, USA "A central question Tobias and Morrison ask and seek to answer as it relates to the course of human thought and ecological outcomes is, “Instead of habituating ourselves to what we do and think, might we have thought and done differently?” Because they ask and ponder so many more thoughtful deep questions, this book is especially satisfying to read, e.g., “. . . How does one species commandeer [a planet] . . . 29.2% of which is land, the rest ocean? Why would we do that? Can philosophical traditions mean anything against the forefront of this unimaginable swath of pathologies that mark our kind?" The sweeping character of Terminal Philosophy Syndrome is stunning, engaging, and fulfilling, making it a mind-expanding tour de force worth reading." - David J. Wagner, PhD, Author, American Wildlife Art; Guest Curator, and adjunct faculty at colleges and universities, and Curator of over fifty art exhibitions  To read these reviews in full, as well as additional commentaries, please CLICK HERE>>>>.
"The sobering new book 'Terminal Philosophy Syndrome' will likely be discomforting. Climate change, while important to reduce and stop as soon as possible, is but one of many things that need close attention. An important message of hope: Everyone, no matter who you are or where you live, can do something to help our troubled planet right now." - Marc Bekoff PhD, Professor Emeritus of Ecology and Evolutionary Biology, University of Colorado, Boulder To read Dr. Bekoff's full interview with the book's authors, Michael Charles Tobias and Jane Gray Morrison, that was recently published in Psychology Today, CLICK HERE>>>>
This treatise is focused on biology and the imponderable; ecosystems lost and found. The problem of human consciousness in the Anthropocene, which is a very different crisis for the planet than ever posed before by our thinking, and the reactive thoughts and feelings of all Others (a word we use to guide one’s image and interior sense of every individual of every other taxonomic rank on earth). We cannot offer something otherwise, that would connote a validation of philosophical speculation. To do so is to live in a falsity, where the authentic, integral and protracted Consciousness that aspires to a facet of biology (and for some, physics) imports every buttress that can attempt to stave off, or at least delay reality, involving itself in everybody’s business, believing fiercely that its very Being matters. When -though who can say – by all evidence it does so only in negative numbers and exponents. In square roots whose expressions are largely disastrous, save for the moments of kindness, the unstinting gestures, first responders, museums, those who have sworn to a Hippocratic Oath in whatever honest and virtuous form, all those cherished byproducts of this unlikely species. Recognition that our species’ capacity to venerate nature in all her quirks and ellipses, stochastic incalculables and steadfast patterns, her graces and unimagined diversity, is our only chance of at least partial survival into an unknown future. Not that it matters in the least, whether we survive as a species, that is. Although, given the currents of our collective behavior – not to be entirely foregone in our conclusions – the one fact that appears to stand out in biological history is that the quicker we are gone, the better it will be. That is not a mean-spirited approach to a text, but a necessarily sobering one.]]>
HMGB1: Functions, Inhibitors and Clinical Significance https://novapublishers.com/shop/hmgb1-functions-inhibitors-and-clinical-significance/ Sun, 04 Dec 2022 14:10:23 +0000 https://novapublishers.com/?post_type=product&p=128197 Eylem Taskin, PhD - Professor, Physiology, Adiyaman University, Adiyaman, Turkey Celal Guven, PhD - Associate Professor, Biophysics, Adiyaman University, Adiyaman, Turkey Salih Tunc Kaya, PhD - Assistant Dr., Biology, Duzce Univeristy, Duzce, Turkey Series: Life Sciences Research and Development BISAC: SCI056000; SCI008000; MED014000 DOI: 10.52305/KNYQ3299 Damage-associated molecular patterns (DAMPs), a term also known as alarmins coined by Walter G. Land, Seong, and Matzinger, are endogenous danger molecules that are released from damaged or dying cells and activate the innate immune system by interacting with pattern recognition receptors (PRRs). One of the most well-known DAMPs is High Mobility Group Box-1 (HMGB1), the name being such due to its very fast movement in gel electrophoresis. Importantly, HMGB1 has been shown to contribute to the pathogenesis of various diseases including myocardial ischemia/reperfusion injury, epilepsy, diabetes, multiple sclerosis, cancer, as well as hepatic steatosis, and fatty liver disease. There are three sections in the book. The first section is named HMGB1 and Cancer, including two chapters. One of the chapters is focused on HMGB1 in cancer therapy and managing COVID-19 infection, as well as multiple sclerosis. The second chapter in the first section is the crosstalk between cancer and myocardial ischemia/reperfusion injury (MIR) through HMGB1 via ferroptotic cell death. The second section is HMGB1 and metabolic interactions, consisting of two chapters. The first chapter is HMGB1 and inflammation in adipose tissue, resulting in insulin resistance and type 2 diabetes. The second chapter in the second section sums up recent data related to HMGB1 and liver injury, e.g., drug-induced liver injury, alcoholic liver disease, non-alcoholic fatty liver disease, viral hepatitis, sepsis, and acute chronic liver failure, hepatocellular death through oxidative stress, inflammatory signaling, and autophagy in hepatocytes. The third section is about HMGB1 and neurodegenerative diseases. The section contains four chapters. The first chapter in the section evaluates HMGB1 and its antagonist in brain disorders, including epilepsy, headache, neuroimmunological disorders, neurodegenerative disorders, and stroke. The second chapter in the third section is about the role of HMGB1 on post-brain injury, including potential mechanisms and therapeutic opportunities as well. The third chapter in the third section evaluates the interaction of HMGB1 and Multiple sclerosis via TLR4/NF-κB signaling pathway, leading to the release of proinflammatory cytokines causing an inflammatory response. The last chapter aims to explain the effects of HMGB1 on epilepsy. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]> Advances in Biology. Volume 2 https://novapublishers.com/shop/advances-in-biology-volume-2/ Fri, 04 Nov 2022 14:00:18 +0000 https://novapublishers.com/?post_type=product&p=128012 Charles D. Grant (Editor) Series: Advances in Biology BISAC: SCI008000 "Advances in Medicine and Biology" presents original research results on the leading edge of medicine and biology research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum.]]> Indian Medicinal Plants of Ladakh Himalaya Used in Sowa Rigpa https://novapublishers.com/shop/indian-medicinal-plants-of-ladakh-himalaya-used-in-sowa-rigpa/ Thu, 03 Nov 2022 20:07:50 +0000 https://novapublishers.com/?post_type=product&p=127802 Mayaram Uniyal - Former Director, CCRAS, Ministry of AYUSH, Government of India, India Deepak Kumar Semwal - Assistant Professor, Uttarakhand Ayurved University, Harrawala, Dehradun, India Ruchi Badoni Semwal - Assistant Professor, Pt. L.M.S. Govt. PG College, Rishikesh, Uttarakhand, India Ankit Kumar - Senior Research Fellow, Uttarakhand Ayurved University, Harrawala, Dehradun, India Series: Herbs and Herbalism BISAC: NAT026000; NAT026000; SCI011000 DOI: 10.52305/BCSO9994
Target Audience This book is useful for common people as well as academicians, scientists and students because the general information about the region, traditional medicinal system and medicinal plants with their uses are well described.
Description This monograph is based on the medicinal plants of Ladakh used in the traditional system of medicine in the Northern part of India, which consists of the Leh and Kargil districts. The medicinal plants described in this book are based on the survey work conducted with the financial support of the Ministry of AYUSH Government of India. Interestingly, there are several species described in this book that are for the first time identified by the author. Although there are many floras used as medicinal plants including some regional floras of India including Indian Medicinal Plants, the flora of indigenous plants of India and some Medicinal plants of Jammu and Kashmir, the present book mainly focuses on the medicinal plants of the Ladakh region used in their traditional medicinal system called Sowa Rigpa or Amchi. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]>
New Research on Mycorrhizal Fungus https://novapublishers.com/shop/new-research-on-mycorrhizal-fungus/ Mon, 24 Oct 2022 19:54:52 +0000 https://novapublishers.com/?post_type=product&p=143239 Qiang-Sheng Wu - Professor, College of Horticulture and Gardening, Yangtze University, China Ying-Ning Zou - Associate professor, College of Horticulture and Gardening, Yangtze University, China Yue-Jun He - Professor, Guizhou University, China Nong Zhou - Professor, Chongqing Three Gorges University. China Series: Microbiology Research Advances BISAC: SCI045000; SCI094000; SCI011000 DOI: 10.52305/GLXN2905 This book focuses on an overview of new advances in mycorrhizal fungi, especially arbuscular mycorrhizal fungi. The book contains chapters on mycorrhizal fungi populations in mangroves, the growth of arbuscular mycorrhizal fungi, mycorrhization of pears in in vitro culture conditions, mycorrhizal mineralization of nutrients, mycorrhizal roles in improving soil health, the benefits of synergistic application of biochar and arbuscular mycorrhizal fungi, and the ecological functions of arbuscular mycorrhizal fungi (invasive plant control, mycorrhizal remediation of soil pollution, and mycorrhizal farm management systems). This book can provide theoretical as well as technical support for researchers working on mycorrhizal fungi, and also provide ideas for new research on mycorrhizal fungi in the future. **Order the printed version and SAVE 50% on the e-book with Print+eBook. Price indicated includes shipping**]]> Properties and Applications of Alginate https://novapublishers.com/shop/properties-and-applications-of-alginate/ Wed, 12 Oct 2022 17:58:07 +0000 https://novapublishers.com/?post_type=product&p=127114 Michael Y. Wilkerson (Editor) Series: Life Sciences Research and Development BISAC: SCI039000 This book includes seven chapters, each focusing on modern research into properties and applications of alginate. The first chapter elucidates the reader to the structural properties and applications of alginate, and additionally discusses future development targets in various fields. The second chapter gives an overview into fabrication of ALG- and S-ALG-based submicron- and nano-sized gel particles with a focus on protein encapsulation. The third chapter returns to analyzing the unique physical properties of alginate and its current and potential uses. The fourth chapter reviews the development of alginate hydrogel beads by the process of microencapsulation, enabling the preservation of the entrapped material. The fifth chapter reviews new uses of alginate in the probiotic food industry as a carrier for probiotic immobilization, and summarizes the extrusion and spray dry techniques used to implement them. The sixth chapter gives a brief knowledge of the structure-property relationships, film formation, biocompatibility, and toxicity study of alginate and its different biomedical applications. The seventh and final chapter, after reviewing how alginate is discovered, describes the main properties of alginate, discusses the sources and chemical structure of alginate, and its various applications, especially in drug release and tissue engineering.]]> Ferns: Growth, Diversity and Ecological Importance https://novapublishers.com/shop/ferns-growth-diversity-and-ecological-importance/ Tue, 27 Sep 2022 17:44:12 +0000 https://novapublishers.com/?post_type=product&p=142113 Shobhit Kumar Srivastava, PhD - Assistant Professor, Department of Botany, Asian International University, Manipur, India Gyan Prakash Srivastava, M.Sc. - Biotechnology, University of Allahabad, Prayagraj, India Series: Life Sciences Research and Development BISAC: SCI011000; NAT034000; NAT011000 DOI: 10.52305/ZDNJ1623 The study of organism evolution and diversity has long drawn the attention of scientists, particularly those working in the various branches of botany. As a result, there are numerous textbooks on the topic. Pteridophytes (Ferns) take up different percentages of the extant texts, and some textbooks even focus on only one subgroup, like the ferns. Currently, no book that comprehensively addresses every crucial aspect related to the development, diversity, and ecological significance of pteridophytes to the best of our knowledge. The authors are confident that the readers of this book will be fascinated by pteridophytes and the range of products they provides, including food, fibers, and ornaments etc. The chapters on the evolution of different plant parts will give the readers new insights into how to investigate more relationships that link the evolution's lingering. All aspects of biodiversity in pteridophytes are covered in the current book, including spore morphology, climate and ecological relationships, ethnobotanical significance, and nematode activity. The remaining two chapters focused on the discourse of these magnificent plants and the cultural relevance of pteridophytes in diverse agro-climatic zones worldwide **Order the printed version and SAVE 50% on the e-book with Print+eBook. Price indicated includes shipping**]]> A Closer Look at Silkworms https://novapublishers.com/shop/a-closer-look-at-silkworms/ Tue, 20 Sep 2022 18:36:40 +0000 https://novapublishers.com/?post_type=product&p=141947 Pratheep Thangaraj, PhD - Department of Biotechnology, PRIST Deemed to be University, Tanjavur, Tamil Nadu, India Series: Insects and Other Terrestrial Arthropods: Biology, Chemistry and Behavior BISAC: NAT005000; NAT017000; SCI025000 DOI: 10.52305/WYEK3748 "Significant progress has been made in the past decade in sericulture research. Sericulture technique covering various aspects has also significantly advanced. Like agriculture, sericulture, as an industry, requires more incredible research and technology development to increase production. This book describes the complete range of subjects with current data relating to mulberry and silkworm. Overall this book emphasizes the fundamental aspects of the stable silkworm crop and various preventive measures against adverse factors. This book deserves 5 stars out of 5. In fact, I would give this book one more star on the rating scale. Highly recommend." - Dr. E. Gayathiri, Assistant Professor, Department of Plant Biology and Plant Biotechnology, Guru Nanak College (Autonomous), Chennai, India
The first section of this book covers recent research developments on the silkworm, B. mori. Chapter One describes the recent advancements in utilization, product diversification and value addition of ericulture resources for the sustainability of farmers. Chapter Two compares the efficacy of silk production and how it is achieved through the growth and development of silkworms supplemented with antioxidants and exposed to low dose radiation from the gamma source. B. mori viral disease and lipid compositional changes during the spinning stage is the focus in the next two chapters. In Chapter Three, Tanmaya et al. review the characteristics of B. mori viruses, the classification of viral infections, mode of infectivity, transmission, symptomatology of viral diseases, detection of pathogenic viruses, the molecular mechanism of pathogenicity of viral diseases and insect antiviral defense mechanisms. Management practices can be carried out both at pre-rearing and rearing conditions for obtaining and improving qualitative and quantitative silk production. Chapter Four analyzes the neutral lipids changes in silk glands during fifth instar larvae and spinning stages of B. mori. Chapter Five, by Geeta Pandey, is an outline of the historical perception of silk, its structure, general characteristics, current clinical trials and emerging biomedical applications of silk fibroin along with future prospects and challenges in this field. The authors of Chapter Six discuss the recent advancements in B. mori lipid metabolism, transportation, and lipid carrier proteins. This book ends with Chapter Seven – a review of silk proteins such as sericin and fibroin and their medical applications. **Order the printed version and SAVE 50% on the e-book with Print+eBook. Price indicated includes shipping**]]>
Transcriptomics and Their Importance https://novapublishers.com/shop/transcriptomics-and-their-importance/ Fri, 16 Sep 2022 16:20:02 +0000 https://novapublishers.com/?post_type=product&p=124084 Sarah Naiyer, PhD - Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA Khalid Hussain Bhat, PhD - Assistant Professor, Division of Basic Sciences and Humanities, FOA,  SKUAST-Kashmir, India Series: Cell Biology Research Progress; Genetics - Research and Issues BISAC: SCI029000; SCI049000 DOI: https://doi.org/10.52305/IZBB7081 “The book entitled Transcriptomics and their Importance is particularly well-written. It is a textbook that beautifully summarizes the history of transcriptomics and compiles the steps involved in the analysis. The book explains intricate technical concepts in understandable language, and it manages to exemplify and summarize often difficult concepts quite nicely.” -  Muhammad Kamran Arif, Senior Research System Analyst, Weil Cornell Medicine, NY USA
Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation. **Order the printed version and SAVE 50% on the e-book with Print+eBook **]]>
Endophytes: Types, Potential Uses and Mechanism(s) of Action https://novapublishers.com/shop/endophytes-types-potential-uses-and-mechanisms-of-action/ Fri, 16 Sep 2022 13:35:24 +0000 https://novapublishers.com/?post_type=product&p=124093 Pragya Tiwari, PhD - Research Professor, Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, Republic of Korea Series: Microbiology Research Advances BISAC: SCI003000; SCI010000 DOI: https://doi.org/10.52305/JETR3242 Endophytes are organisms that live between living plant cells and do not cause disease. Endophytes are ubiquitously present in diverse plant species, demonstrating a co-evolution with the plant host. Furthermore, different classes of microbial species, including bacteria, fungi, and actinomycetes colonize the internal plant tissues, leading to a wide range of implications. The medicinal plants associated with endophytes have been extensively studied as a potential source of bioactive compounds, with pharmacological attributes and biotechnological applications. Scientific breakthroughs in whole genome sequencing and annotation of endophyte-associated gene/metabolic pathways provided key insights into functional mechanisms and their dynamics within plants. Studies have highlighted the socio-economic implications of fungal endophytes in the environment, agriculture, and medicine with considerable success. Although extensively studied as a “production platform” of novel pharmacological metabolites, the molecular mechanisms of plant-endophyte dynamics remain less understood/explored for their efficient utilization in drug discovery and other biotechnological applications. This book aims to provide comprehensive knowledge about the multifaceted applications of endophytes. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]> Advances in Animal Science and Zoology. Volume 20 https://novapublishers.com/shop/advances-in-animal-science-and-zoology-volume-20/ Fri, 02 Sep 2022 13:03:25 +0000 https://novapublishers.com/?post_type=product&p=124655 Owen P. Jenkins (Editor) Series: Advances in Animal Science and Zoology BISAC: SCI070000 This volume includes six chapters that present updates in animal science and zoology. Chapter One examines the use of zebrafish model system to investigate the pathophysiology of schizophrenia. Chapter Two consolidates facts about melatonin and its involvement in the regulation of fish populations. Chapter Three explores the interaction between the native aquatic gastropod, Valvata humeralis, and invasive aquatic gastropod, Potamopyrgus antipodarum, along a biotic gradient of density in a system where it was suspected that an interaction shift was occurring. Chapter Four explores competition and facilitation between these two gastropods. Chapter Five analyzes the role of superoxide dismutase in reptiles under toxicity contexts. Lastly, Chapter Six analyzes and assesses the corpses of three English Bulldog puppies that had anasarca, a fetal malformation that presents generalized edema.]]> Advances in Biology. Volume 1 https://novapublishers.com/shop/advances-in-biology-volume-1/ Thu, 01 Sep 2022 19:16:14 +0000 https://novapublishers.com/?post_type=product&p=124664 Charles D. Grant (Editor) Series: Advances in Biology BISAC: SCI008000 This volume includes seven chapters that describe recent advances in biology. Chapter One reviews and discusses the enzymes and methods for bioproduction of the rare sugars of D-allulose, D-allose, allitol, L-xylulose, L-xylose, and L-ribose. Chapter Two analyzes the properties of mKATP channels and functional and bioenergetic effects of ATP-sensitive K+ transport. Chapter Three describes interactions of bilirubin with several proteins and the effects of these interactions on the protein’s structure and function. Chapter Four provides an overview of Panton Valentine Leukocidin-producing Staphylococcus Aureus pneumonia and its therapeutic strategy. Chapter Five discusses the reunification of chemical and biochemical thermodynamics. Chapter Six includes a study of the in-vitro activity of eftolozane/tazobactam against pseudomonas aeruginosa and enterobacterales isolates from Taiwan. Finally, Chapter Seven examines elevated levels of caspase-3 in cerebrospinal fluid of newborns with perinatal asphyxia as a biomarker of failing mitochondrial bioenergetics.]]>