https://novapublishers.com Publisher of Books and Journals in Medicine and Health, Science and Technology and Social Sciences Fri, 10 Feb 2023 20:03:12 +0000 en-US hourly 1 https://wordpress.org/?v=6.1.1 https://novapublishers.com/wp-content/uploads/2018/08/cropped-nova-favicon-32x32.jpg https://novapublishers.com 32 32 https://novapublishers.com/shop/exercise-and-diet-as-modulators-of-cognitive-function-through-gut-microbiota/ Mon, 24 Oct 2022 18:04:43 +0000 https://novapublishers.com/?post_type=product&p=126457 Natalia Arias, PhD - Head of Research and Professor at the Faculty of Life and Nature Sciences, Nebrija University, Hoyo de Manzanares, Madrid, Spain Ismael Martínez-Guardado, PhD - Associated Professor at the Faculty of Life and Nature Sciences, Nebrija University, Spain Francisco J. Grijota Pérez, PhD - Associated Professor at the Faculty of Life and Nature Sciences, Nebrija University, Spain Series: Gastroenterology Research and Clinical Developments BISAC: MED031000 DOI: https://doi.org/10.52305/IVVF7328 Target Audience: This is a useful resource for university students and researchers in the life sciences, sport sciences, medicine and related fields. In recent years, the study of the human intestinal microbiota and its relationship with the brain has expanded enormously in the scientific field. It has been shown that changes in nutritional habits, apart from producing changes in the host microbiota, can affect the central nervous system, contributing to the development of neurological pathologies such as Parkinson's, Alzheimer's and motor neuron disorders. Several studies have shed light into the role of exercise as a preventive factor against various diseases; however, exercise can also produce stress on the body. This book discusses the relevance of an individual's health state, type and duration of exercise, and diet as contributing factors to the microbiota-gut-brain axis. Also, this book presents findings regarding the relationships between epigenetic modifications and the gut microbiota as well as between epigenetics and cognitive function. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]> https://novapublishers.com/shop/gut-microbiome-simplified-for-medical-nursing-nutrition-students-and-practitioners/ Mon, 27 Jun 2022 18:51:42 +0000 https://novapublishers.com/?post_type=product&p=127106 Ujjwal Sonika, MD, DM - Associate Professor, Gastroenterology, GB Pant Hospital, Maulana Azad Medical College, New Delhi, India Series: Gastroenterology Research and Clinical Developments BISAC: MED000000; MED024000; DOI: MED03100010.52305/GBKU2379 "I loved reading this book and appreciate the way complex concepts are made extremely simple. A must-read for everyone who wants to understand the gut microbiome." - Vishal Sharma, Associate Professor, Gastroenterology, PGIMER, Chandigarh, India "An excellent book! Written from a healthcare professional’s viewpoint." - Vipin Gupta, Consultant Gastroenterologist, North Bristol Trust, Bristol, UK

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If you are a health-care provider or a student who wants to understand the basics of the gut microbiome, this book is for you. If you find the scientific or media content on the gut microbiota confusing and perplexing, this book will provide you with the armamentarium to better understand it, and if you wish to know the current use of gut microbiota therapies in your field of expertise, this book gives you that concisely. All the information provided is based on the latest published scientific literature. This book presents you with a gist of more than 1,000 research publications. This book explains in an easy way the current terminologies used in the field of gut microbiome, the methods to study gut microbiota, and its role in various diseases. Concise but up-to-date sections are also included on the gut fungi and viruses. Each chapter is neatly divided into the subsections of biological plausibility and evidence from animal studies, followed by evidence from human studies and clinical trials. Such an exercise builds a clear picture in the reader’s mind regarding the importance of the gut microbiome in each disorder. The current status of gut microbiota therapies is provided at the end of each chapter. A separate chapter is also included for the microbiota therapies including prebiotics, probiotics, postbiotics, and FMT. It explains and discusses their advantages, shortcomings and clinical applications. Apart from gut microbiota, the reader will develop a better understanding of concepts such as endotoxemia, inflammation, insulin resistance, stress and its biology, atherosclerosis, and immune function. All of these are highly relevant to fully grasping the pathophysiology of various diseases. A better understanding leads to a better cure. This book is written by a clinician and thus is easier to understand and provides ready-to-use clinically relevant information. **Order the printed version and SAVE 50% on the e-book with Print+eBook**]]> https://novapublishers.com/shop/effects-of-healthful-bioactive-compounds-on-the-gastrointestinal-tract/ Sun, 01 May 2022 13:15:58 +0000 https://novapublishers.com/?post_type=product&p=115155 Series: Gastroenterology Research and Clinical Developments BISAC: MED031000; HEA039010 DOI: https://doi.org/10.52305/YUYD5491 Target Audience: The editors hope that the book will be a useful reference for researchers, product developers, health professionals and students. Optimal performance of the liver and gastrointestinal tract is vital for general human health. The gastrointestinal system is the main site of nutrient digestion and absorption, and therefore has substantial effects on providing energy and growth for the body. All nutrient and non-nutrient components have an impact on the gastrointestinal system, either locally or systemically. Undeniably, gastrointestinal disorders, with increasing lifetime prevalence, have a profound effect on human health and reduce the quality of life. Nowadays, therapeutic options are limited to medical therapy, including pharmacologic approaches and surgical intervention or lifestyle changes aimed at dietary modifications and increased physical activity. Certainly, dietary modifications can be effective in preventing, treating, and alleviating associated symptoms and complications. In addition to improving whole dietary patterns, the components of foods, collectively or independently, also have a substantial role in their therapeutic features. These components, particularly bioactive compounds, confer unique health benefits and aid in management of various diseases. Recently, investigators have paid much attention to chemopreventive activity of bioactive dietary compounds in the treatment and prevention of gastrointestinal diseases. Fruits, vegetables and edible plants are the main source of biologically active compounds with anti-inflammatory, antioxidant, and protective properties. Most importantly, no major side effects have been reported for these compounds until now. Therefore, this book offers novel targets for prevention, treatment and management of liver and gastrointestinal diseases by providing evidence of effectiveness of bioactive compounds of functional foods. Furthermore, intracellular and molecular pharmacological mechanisms of action of bioactive compounds will also be discussed. It seems that bioactive compounds bring new hope for patients with gastrointestinal disorders through their anti-inflammatory and anti-oxidative potential. **Order both the printed version and the e-book together and SAVE!**]]> https://novapublishers.com/shop/probiotics-and-their-role-in-health-and-disease/ Tue, 27 Jul 2021 20:24:18 +0000 https://novapublishers.com/?post_type=product&p=101864 Yusuf Olsen (Editor) Series: Gastroenterology Research and Clinical Developments BISAC: MED031000 Probiotics are live microorganisms that, when consumed, can provide health benefits, generally by improving or restoring the gut flora. As probiotics have become increasingly popular in recent years, it is important for consumers and clinicians to understand the details of the potential health effects of these supplements. Chapter 1 focuses on the relationship between different types of milk, the growth of probiotics, and relevant characteristics regarding viability, the quality of the dairy product, and the production of undesirable components. Chapter 2 summarizes studies on the probiotic impact of functional foods on the immune system and analyzes the future of the probiotic functional food market. Chapter 3 describes pathways and mechanisms through which probiotics may improve hypothyroidism and its complications. Chapter 4 presents a literature review of intestinal microbiota and bone health and discusses the effectiveness of probiotics in the treatment and prevention of osteoporosis. Chapter 5 presents an FTIR analysis of protein/peptide-based biopolymers used for probiotic encapsulation. Lastly, Chapter 6 collates experimental studies on probiotics with ameliorative effects on arsenic toxicity.]]> https://novapublishers.com/shop/gut-bacteria-the-secret-to-health/ Wed, 16 Dec 2020 17:12:53 +0000 https://novapublishers.com/?post_type=product&p=89877 Series: New Developments in Medical Research BISAC: SCI006000 This book summarizes the latest scientific research around the influence of gut bacteria on health and well-being as well as their impact on lifestyle diseases. Information is presented in easy-to-understand language and is interspersed with fun facts and anecdotal accounts, which help the audience acquire this fundamental and relevant scientific knowledge. The authors explain the influence of gut bacteria on physical and mental well-being in language friendly to laypeople. They then share insights about the role of gut bacteria in various lifestyle diseases such as diabetes, obesity, and metabolic syndrome utilizing the latest published research in peer-reviewed journals. The information provided in this book is useful to anyone who wants to lead a healthy life. It is worth reading even for health care professionals as their current curriculum does not entail extensive information about gut bacteria and their significance in health.]]> https://novapublishers.com/shop/dysbiosis-a-study-of-underlying-causes/ Thu, 25 Jun 2020 14:06:33 +0000 https://novapublishers.com/?post_type=product&p=75473 Richard I. Cowell (Editor) Series: New Developments in Medical Research BISAC: MED031000 Dysbiosis: A Study of Underlying Causes includes studies aimed at determining design interventions in which the composition of microbiota may be modulated to achieve a specific microbial profile beneficial to overall host behavior. In addition, this compilation summarizes and critically discusses recent literature on the evaluation of changes in the microbiota associated with liver diseases, aiming to evaluate which alterations could be involved in the initiation and progression of liver disease. The authors emphasize the importance of promoting a balanced microbiome to maintain or improve oral health effectively. In order to fully understand the progression of oral diseases, it is essential to evaluate the microbiome together with genetic, immunological and environmental factors.]]> https://novapublishers.com/shop/helicobacter-pylori-from-diagnosis-to-treatment/ Tue, 23 Jun 2020 13:21:01 +0000 https://novapublishers.com/?post_type=product&p=74644 Alexandra Curr (Editor) Series: Digestive Diseases - Research and Clinical Developments BISAC: MED022090, MED031000 Helicobacter pylori is classified as a gram-negative, spiral and microaerophilic bacterium and considered one of the most common causes of gastric infections worldwide. It was isolated from gastric biopsy specimens from patients with chronic gastritis and peptic ulcers in 1983. Non-pylori Helicobacter species may occasionally colonize the human stomach causing gastritis, but the prevalence is unknown. As such, in this compilation antral biopsies from 484 patients were examined for H. pylori by culture and quantitative polymerase chain reaction. In addition, the biopsies were examined for Helicobacter spp. by polymerase chain reaction. The authors summarize and compare the historical and novel methods used for the diagnosis and treatment of H. pylori infection. This collection goes on to assess how knowledge about the characteristics, advantages, and limitations of various diagnostic methods for H. pylori allows for the choice of the appropriate technique in the clinical practice or research setting. Lastly, the authors propose that every child with suspected H. pylori infection should be carefully evaluated by a pediatric gastroenterologist before deciding whether to perform upper gastrointestinal endoscopy and any eradication therapy. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/gastrointestinal-infectious-diseases/ Thu, 14 May 2020 18:17:43 +0000 https://novapublishers.com/?post_type=product&p=69516 Hyasinta Jaka (Editor) Department of Internal Medicine, Bugando Medical Centre and Catholic University of Health and Allied Sciences Mwanza, Tanzania Series: Digestive Diseases - Research and Clinical Developments BISAC: MED031000 Gastrointestinal infection most often affects low-income populations in developing regions of Asia, the Americas and Africa. It is one of the tropical infections caused by different organisms. The risks are very high in areas where there is poor sanitation, living conditions and poor handling of food and water. . This book covers the GIT infection and all the topics will be beneficial to medical students and clinicians in managing their patients and taking measures to prevent infections. This book covers the diseases and complications of the infection. The diagnostic tests for different infectious diseases have been covered in depth to give wide knowledge to the readers on the new diagnostic technique and cheap tests, which can be done in resource-limited areas. The book will also cover the different international treatment guidelines in treating the infection and the challenges in the eradication in this era of multidrug resistance. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/diverticulitis-diagnosis-and-treatment/ Thu, 23 Apr 2020 13:10:23 +0000 https://novapublishers.com/?post_type=product&p=73679 Shams-ul-Bari (Editor) Associate professor, Department of surgery, SKIMS, Medical College Srinagar, Kashmir, India Ajaz A. Malik (Editor) Department of Surgery, Sherikashmir Institute of Medical Sciences, Srinagar Jammu and Kashmir, India Series: New Developments in Medical Research BISAC: MED031000 Over past several decades, an increasing number of cases of diverticulitis of colon have been reported making it a major health problem particularly in western countries. The distribution of the disease varies geographically with western population having prevalence rates of 5-45% and Asian population having prevalence rates of 13-25%. Although elderly people are more likely to develop diverticulitis, younger patients may also develop diverticular disease. In fact, it has been reported that disease in younger patients is more aggressive with higher rates of complication and recurrence. According to latest statistical reports acute diverticulitis accounts to nearly 200000 hospital admissions putting a burden of 2.7 billion dollars on healthcare system in America. Diverticular disease can cause significant symptoms, impair quality of life and can prove fatal if left untreated and is considered as the fifth most costly gastrointestinal disorder in the Western world. The book entitled, Diverticulitis; Diagnosis and Treatment, presents an up to date review of the medical and surgical management of diverticulitis. The book comprises of various topics discussing the background, epidemiology, etiology, pathogenesis, presentation, treatment both medical and surgical, and recent advances in the management of diverticulitis. The book will be academic interest for surgeons, physicians, gastroenterologists and Coloproctologists. The book can be used as a reference book by teachers, professionals and students. The main benefit of reading this book is that since this disease entity is common all over the world and its incidence is increasing and is a significant contributor of health care costs, all the relevant and latest information regarding this disease has been published in a comprehensive form which will be helpful to the students, academicians, researchers and professionals dealing with medical healthcare. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/colitis-causes-diagnosis-and-treatment/ Tue, 05 Nov 2019 13:56:01 +0000 https://novapublishers.com/?post_type=product&p=61302 Soren Garcia (Editor) Series: Digestive Diseases - Research and Clinical Developments BISAC: MED031000 Clostridium difficile and its toxin-producing strains are the most common causative agents of Clostridium difficile infections. It is an inflammatory bowel disease predominantly caused by prior antibiotic treatment. The use of broad spectrum antibiotics suppresses bacterial intestinal microflora and causes overgrowth of the Clostridium difficile, and often occurs in immunocompromised, older and polymorbid patients. Following this, the authors discuss inflammatory bowel disease (including ulcerative colitis), a complex, multifactorial disease of unknown etiology. Intestinal sulfate-reducing bacteria, especially Desuflovibrio, are often found in the intestines and feces of people and animals with inflammatory bowel disease. Of late, the incidence of autoimmune colitis both in adults and children has been progressively increasing globally. The efficacy of conventional therapeutic measures is questionably limited due to short-term immunosuppressive effect along with possible serious side effects. As such, the authors present evidence from epidemiological studies that has demonstrated an inverse relationship between the occurrence of parasitic diseases and various autoimmune pathologies. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/diverticular-disease-colonic-epidemy-of-the-21st-century/ Thu, 03 Oct 2019 11:55:55 +0000 https://novapublishers.com/?post_type=product&p=48732 Series: Digestive Diseases - Research and Clinical Developments BISAC: MED031000 Diverticular disease is one of the most common problems encountered by gastroenterologists, emergency physicians and surgeons, with a higher prevalence in elderly patients and a dramatic rising of incidences in young people, which involve an increase in health care costs, according to ambulatory visits and hospital admissions. Acute diverticulitis, the most important complication of diverticular disease, has a broad spectrum of severity, which involves many treatment options, ranging from outpatient-based antibiotic treatment, or even isolated nonsteroidal anti-inflammatory drugs, to parenteral antibiotic regimen, percutaneous drainage or surgery (lavage and drainage, Hartmann procedure or resection with anastomosis with or without a diverting stoma). The American Society of Colon and Rectal Surgeons recommended in their guidelines a routine follow-up colonoscopy after recovery from an acute episode to rule out malignancy, which is being re-evaluated in recent studies, including the alternative CT-colonography, especially in cases of incomplete colonoscopy or in high-risk patients. After an episode of acute diverticulitis, there is a significant risk of recurrence and a negative impact on quality of life. In order to decrease it, there are many treatments that are being evaluated such as fiber-rich diet, mesalazine, rifaximin, probiotics and elective colon resection, which should be decided individually. The aim of this book is to revise the current evidence about the diverticular disease and acute diverticulitis. (Imprint: Nova Medicine and Health)]]> https://novapublishers.com/shop/candida-albicans-symptoms-diagnosis-and-treatment/ Tue, 23 Jul 2019 13:08:36 +0000 https://novapublishers.com/?post_type=product&p=36571 Nayira.S.S (Editor) Associate Professor, Majmaah University, Saudi Arabia Series: Immunology and Immune System Disorders BISAC: MED031000 Candida albicans is an opportunistic pathogenic yeast and it is a common member of the human gut flora. It does not proliferate outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism but can become pathogenic in immunocompromised individuals under a variety of conditions. Yeast infection is caused by a specific strain of yeast known as Candida. Although a small amount of yeast is found in the body, yeast infection occurs when there is an overgrowth of Candida. Most yeast infections is caused by Candida albicans. Fungal that affects different areas of the body like skin, mouth, genitals, throat and blood. The yeast Candida albicans lives inside every one of us. Normally it presents no problems, but today’s widespread use of broad-spectrum antibiotics, antacids, contraceptive pills, and steroids, as well as the all-too-common sugar-rich diet, can lead to a proliferation of this parasitic yeast within the body. Often overlooked by doctors, overgrowth of Candida has been linked to a wide variety of physical and mental problems such as: • acne • heartburn • muscular pain • anxiety • irritable bowel syndrome (IBS) • fibromyalgia • bloating and constipation • chronic fatigue • migraine • cystitis irritable bowel syndrome (IBS) • allergies • menstrual problems • irritability Candida that causes the human infection candidiasis results from an overgrowth of the fungus is for example often observed in HIV-infected patients. C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. C. albicans, C. tropicalis, C. parapsilosis, and C. glabrata are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. Invasive candidiasis contracted in a hospital causes 2,800 to 11,200 deaths yearly in the U.S. C. albicans is commonly used as a model organism for biology. It is also known as sweet fungus and sugar inhibits its growth. It is generally referred to as a dimorphic fungus because it grows both as yeast and filamentous cells. However, it has several different morphological phenotypes. C. albicans was for a long time considered an obligate diploid organism without a haploid stage. This is, however, not the case. Next to a haploid stage C. albicans can also exist in a tetraploid stage. The latter is formed when diploid C. albicans cells mate when they are in the opaque form. Candida thrives well on sugar and needs an acidic environment to survive. Processed and refined foods high in gluten and sugar (including natural sugars) create an ideal home for Candida, so the most logical place to start battling the enemy is by restricting intake of alcohol, sweets, bread, vinegar and foods containing vinegar, peanuts and foods high in sugar — including sweet fruits such as bananas and dates. Include protein rich foods like avocados, chia seeds and wild-caught fish. Garlic and turmeric (also known as curcumin) is a natural anti-fungal that can kill Candida. The best potent and all-natural candida killer is coconut oil. It contains caprylic acid, which has anti-microbial properties that can kill yeasts and candida. Studies have shown that it is more effective in treating candidiasis than the prescription drug fluconazole. There are relatively few drugs that can successfully treat Candidiasis. Treatment commonly includes amphotericin B,echinocandin, or fluconazole for systemic infections. Nystatin for oral and esophageal infection and Clotrimazole for skin and genital yeast infections. (Imprint: Nova Medicine and Health)]]>